Detalhe da pesquisa
1.
IL-4 Predicts the Efficacy of a Candidate Antioxycodone Vaccine and Alters Vaccine-Specific Antibody-Secreting Cell Proliferation in Mice.
J Immunol
; 210(9): 1272-1280, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36939374
2.
Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders.
J Immunol
; 207(3): 860-867, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34281999
3.
Pharmacological Profiling of Antifentanyl Monoclonal Antibodies in Combination with Naloxone in Pre- and Postexposure Models of Fentanyl Toxicity.
J Pharmacol Exp Ther
; 381(2): 129-136, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35153198
4.
A Membrane-Modulated Centrifugal Microdevice for Enzyme-Linked Immunosorbent Assay-Based Detection of Illicit and Misused Drugs.
Anal Chem
; 93(48): 16213-16221, 2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34807557
5.
Monoclonal Antibodies Counteract Opioid-Induced Behavioral and Toxic Effects in Mice and Rats.
J Pharmacol Exp Ther
; 375(3): 469-477, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980813
6.
Glycogen Synthase Kinase 3 (GSK-3)-mediated Phosphorylation of Uracil N-Glycosylase 2 (UNG2) Facilitates the Repair of Floxuridine-induced DNA Lesions and Promotes Cell Survival.
J Biol Chem
; 291(52): 26875-26885, 2016 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875297
7.
Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination.
Mol Pharmacol
; 89(1): 53-62, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494862
8.
The fentanyl-specific antibody FenAb024 can shield against carfentanil effects.
Toxicol Lett
; 396: 1-10, 2024 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588756
9.
Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C).
bioRxiv
; 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659969
10.
Anti-Strychnine Immunoconjugate Reduces the Effects of Strychnine-Induced Toxicity in Mice.
ACS Chem Neurosci
; 14(7): 1291-1298, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36952479
11.
Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure
; 31(1): 20-32.e5, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36513069
12.
A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Cell Rep
; 42(2): 112049, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719797
13.
Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development.
Hum Vaccin Immunother
; 18(6): 2122507, 2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194773
14.
Preclinical Efficacy and Selectivity of Vaccines Targeting Fentanyl, Alfentanil, Sufentanil, and Acetylfentanyl in Rats.
ACS Omega
; 7(19): 16584-16592, 2022 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35601290
15.
Therapeutic and Prophylactic Vaccines to Counteract Fentanyl Use Disorders and Toxicity.
J Med Chem
; 63(23): 14647-14667, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33215913
16.
Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders.
Hum Vaccin Immunother
; 15(4): 909-917, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30625019
17.
Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose.
Sci Rep
; 8(1): 5508, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615715
18.
Vaccines to treat opioid use disorders and to reduce opioid overdoses.
Neuropsychopharmacology
; 44(1): 217-218, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30405185